Sam Garfinkle

Sam Garfinkle

MD/PhD student

I am a first-year MD/PhD student in the Biochemistry and Molecular Biophysics (BMB) graduate group at Penn.

I graduated from Princeton University with an A.B. in Chemistry, magna cum laude, and a certificate in Quantitative and Computational Biology. At Princeton, I completed my senior thesis research in the lab of Todd Hyster, where I determined high-resolution crystal structures of flavoenzymes and used protein engineering techniques for the development of asymmetric biocatalysts.

I also completed research in the lab of John T. Groves, where I worked on Mn-salen catalyzed sp3 C-H isocyanation reactions.

Most recently, I spent two years working at D.E. Shaw Research, where I applied molecular dynamics simulations and computational methods to an array of drug discovery and basic science projects, including the development of a cancer drug currently in Phase I clinical trials.